1802220-02-5 repotrectinib

Lastnosti

Videz bel do belo-kristalno trdne
Gostota 1,46 ± 0. 1 g/cm3
Shranjevalna temperatura. Shranjujte v -20
tvorijo kristalno trdno snov
PKA1 0. 79 ± 0,60
 

Vloga:

Repotrectinib, je zdravilo proti raku, ki se uporablja za zdravljenje nedrobnoceličnega pljučnega raka. Repotrectinib je inhibitor onkogenske tirozin proteina kinaze ROS1 (ROS1) in tropomiozinskega receptorja tirozin kinaze (TRK) TrKA, Trkb in Trkc.

 

Sinonime:

Repotrectinib

1802220-02-5

Ropotrekktinib

repotrectinib

(3r, 11s) -6- fluoro -3, 11- dimethyl -10- oxa -2, 13,17,18, 21- pentazatetracy CLO [13.5.2.04,9.018,22] Docosa -1 (21), 4 (9), 5,7,15 (22), 16, 19- heptaen -14- ena

TRX -0005

1, 15- etheno -1 H-pyrazolo (4, 3- f) (1,4,8,10) benzoxatriazacyclotridecin -4 (5H) -One 11- fluoro -6, 7,13, 14- tetrahydro -7, 13-, dimethyl-, (7s, 13r)-

(13e, 14e, 3r, 6s) -45- fluoro -3, 6- dimetil -5- oxa -2, {{9} diaza -1 (5,3) -Pyrazolo [1, 5- a] Pyrimidina -4 (1,2) -Benzenaclononaphan -9- one

(1z) -6- fluoro -3, 11- dimethyl -10- oxa -2, 13,17,18, 21- Pentaazatet Racyclo (13.5.2.04,9.018,22) Docosa -1, 4,6,8,15,19, 21- heptaen -14- one

1, 15- etheno -1 H-pyrazolo (4, 3- f) (1,4,8,10) benzoxatriazacyclotridecin -4 (5H) -One 11- fluoro -2, 6,7, 13- tetrahydro -7, 13- dimetil-, (14z)-(14z)-(14z)

Primer 93 (US20170334929A1)

(7s, 13r) -11- fluoro -7, 13- dimethyl -6, 7,13, 14- tetrahydro {9}}, {{10}, {{10} } Ethenopirazolo [4, 3- f] [1,4,8,10] benzoxatriazacyclotridecin -4 (5H) -one

 

Priljubljena oznake: 1802220-02-5 repotrectinib, Kitajska 1802220-02-5 Proizvajalci, dobavitelji